Cellular and molecular mechanisms of fibrosis
نویسندگان
چکیده
منابع مشابه
[Cellular and molecular mechanisms of fibrosis].
Fibrosis is defined by the overgrowth, hardening, and/or scarring of various tissues and is attributed to excess deposition of extracellular matrix components including collagen. Fibrosis is the end result of chronic inflammatory reactions induced by a variety of stimuli including persistent infections, autoimmune reactions, allergic responses, chemical insults, radiation, and tissue injury. Al...
متن کاملMolecular and cellular mechanisms of pulmonary fibrosis
Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary fibrosis is considered the most common and severe form of the disease, with a median survival of approximately three years and no proven effective therapy. Despite the fact that effective treatments are absent and the pr...
متن کاملO14: Cellular and Molecular Mechanisms of Spinal Cord Trauma
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملCellular and molecular mechanisms in kidney fibrosis.
Fibrosis is a characteristic feature of all forms of chronic kidney disease. Deposition of pathological matrix in the interstitial space and within the walls of glomerular capillaries as well as the cellular processes resulting in this deposition are increasingly recognized as important factors amplifying kidney injury and accelerating nephron demise. Recent insights into the cellular and molec...
متن کاملCellular and Molecular Mechanisms of Chronic Inflammation-Associated Organ Fibrosis
Organ fibrosis is a pathological condition associated with chronic inflammatory diseases. In fibrosis, excessive deposition of extracellular matrix (ECM) severely impairs tissue architecture and function, eventually resulting in organ failure. This process is mediated primarily by the induction of myofibroblasts, which produce large amounts of collagen I, the main component of the ECM. Accordin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Pathology
سال: 2008
ISSN: 0022-3417,1096-9896
DOI: 10.1002/path.2277